The history of Bethlem

نویسنده

  • Andrew Scull
چکیده

Till now, the only comprehensive history of the most famous asylum in the Englishspeaking world has been a rare volume produced by the hospital's one-time chaplain E G O'Donoghue, The story of Bethlehem Hospitalfrom itsfoundation in 1247, which was published in 1914.1 To coincide with the institution's 750th anniversary, Routledge have produced another one-volume history, the product this time of the collective labours of two very famous social historians, Roy Porter and Asa Bfiggs, and three younger colleagues. Eighty years ago, the charity's governors purchased and distributed 2,000 copies of O'Donoghue's idiosyncratic romp through their institution's past. It is extremely doubtful that their present-day successors will follow suit, not because the professional historians' production is less hagiographic and flattering to their sensibilities-though at least intermittently it is-but rather on purely financial grounds. Astonishingly, and in an appalling demonstration of self-defeating rapaciousness, Routledge have elected to charge a stratospheric price for a plainly produced volume of some 750 pages, accompanied by less than three dozen black and white illustrations. At retail, one would be expected to pay the princely sum of £300,000 for a couple of thousand copies of their product! At this price, in a few years' time,

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منابع مشابه

Bethlem myopathy in a Taiwanese family.

We report three cases of Bethlem myopathy from three consecutive generations of a Taiwanese family, including one woman aged 70, one man aged 40, and a boy aged 8. The clinical features of the patients included autosomal dominant inheritance, childhood or adolescent onset, mainly proximal and extensor involvement, early diffuse joint contractures, and absence of cardiac involvement. These featu...

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Evidence for locus heterogeneity in the Bethlem myopathy and linkage to 2q37.

The Bethlem myopathy, a childhood onset autosomal dominant myopathy with joint contractures, has recently been localized to 21q in a series of Dutch families and the alpha 1 and alpha 2 subunits of type VI collagen (COL6A1 and COL6A2) have been postulated as candidate genes. We investigate a large family of French Canadian descent (family 1489) in which the Bethlem myopathy is segregating. Fami...

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Molecular Genetic Diagnosis of a Bethlem Myopathy Family with an Autosomal-Dominant COL6A1 Mutation, as Evidenced by Exome Sequencing

BACKGROUND We describe herein the application of whole exome sequencing (WES) for the molecular genetic diagnosis of a large Korean family with dominantly inherited myopathy. CASE REPORT The affected individuals presented with slowly progressive proximal weakness and ankle contracture. They were initially diagnosed with limb-girdle muscular dystrophy (LGMD) based on clinical and pathologic fe...

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Illustrations from the Wellcome Institute Library. John Monro MD and Charles James Fox: etching by Thomas Rowlandson.

THE picture reproduced in Fig. 1 is an unsigned etching dated 4 April 1784, which is firmly attributed on stylistic grounds to Thomas Rowlandson (1756-1827).' The two figures depicted are identified as, on the left the Bethlem mad-doctor John Monro (1715-1791), and on the right the politician Charles James Fox (1749-1806). Dr Monro screws up his right eye as he raises a lens to his left and dec...

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Spontaneous keloid formation in patients with Bethlem myopathy.

A 32-year-old woman and a 50-year-old man with clinically typical Bethlem myopathy developed seemingly spontaneous keloids on their shoulder region (figure). The patients did not recall any significant trauma to the skin of this region. Bethlem myopathy (MIM #158810) is caused by dominant and recessive mutations in the collagen VI genes: COL6A1, COL6A2, and COL6A3. Skin manifestations include h...

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Ullrich congenital muscular dystrophy and Bethlem myopathy: clinical and genetic heterogeneity.

UNLABELLED Ullrich congenital muscular dystrophy (UCMD), due to mutations in the collagen VI genes, is an autosomal recessive form of CMD, commonly associated with distal joints hyperlaxity and severe course. A mild or moderate involvement can be occasionally observed. OBJECTIVE To evaluate the clinical picture of CMD patients with Ullrich phenotype who presented decreased or absent collagen ...

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عنوان ژورنال:
  • Medical History

دوره 43  شماره 

صفحات  -

تاریخ انتشار 1999